![Differences in CD80 and CD86 transendocytosis reveal CD86 as a key target for CTLA-4 immune regulation | Nature Immunology Differences in CD80 and CD86 transendocytosis reveal CD86 as a key target for CTLA-4 immune regulation | Nature Immunology](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fs41590-022-01289-w/MediaObjects/41590_2022_1289_Fig3_HTML.png)
Differences in CD80 and CD86 transendocytosis reveal CD86 as a key target for CTLA-4 immune regulation | Nature Immunology
Binding of CD80/CD86 and cytotoxic T-lymphocyte-associated protein 4... | Download Scientific Diagram
![Immunomodulation of human intestinal T cells by the synthetic CD80 antagonist RhuDex® - Heninger - 2014 - Immunity, Inflammation and Disease - Wiley Online Library Immunomodulation of human intestinal T cells by the synthetic CD80 antagonist RhuDex® - Heninger - 2014 - Immunity, Inflammation and Disease - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/40535b99-fbe7-4df2-93fd-7538fced1204/iid334-fig-0001-m.jpg)
Immunomodulation of human intestinal T cells by the synthetic CD80 antagonist RhuDex® - Heninger - 2014 - Immunity, Inflammation and Disease - Wiley Online Library
![3 CD80 and CD86 deliver bidirectional signaling for the activation of T... | Download Scientific Diagram 3 CD80 and CD86 deliver bidirectional signaling for the activation of T... | Download Scientific Diagram](https://www.researchgate.net/publication/274386360/figure/fig2/AS:978234644631553@1610240722589/CD80-and-CD86-deliver-bidirectional-signaling-for-the-activation-of-T-cell-and-APC.png)
3 CD80 and CD86 deliver bidirectional signaling for the activation of T... | Download Scientific Diagram
![Frontiers | The Association Between CTLA-4, CD80/86, and CD28 Gene Polymorphisms and Rheumatoid Arthritis: An Original Study and Meta-Analysis Frontiers | The Association Between CTLA-4, CD80/86, and CD28 Gene Polymorphisms and Rheumatoid Arthritis: An Original Study and Meta-Analysis](https://www.frontiersin.org/files/Articles/598076/fmed-08-598076-HTML/image_m/fmed-08-598076-g001.jpg)
Frontiers | The Association Between CTLA-4, CD80/86, and CD28 Gene Polymorphisms and Rheumatoid Arthritis: An Original Study and Meta-Analysis
![2 CD80/CD86 deliver bidirectional signaling for the activation of T... | Download Scientific Diagram 2 CD80/CD86 deliver bidirectional signaling for the activation of T... | Download Scientific Diagram](https://www.researchgate.net/publication/274386280/figure/fig2/AS:978234418151425@1610240668507/CD80-CD86-deliver-bidirectional-signaling-for-the-activation-of-T-cell-and-APC-Cognate.jpg)
2 CD80/CD86 deliver bidirectional signaling for the activation of T... | Download Scientific Diagram
![This study identified key differences in transendocytosis by CTLA-4 when activated by CD80 and CD86 ligands; whereby CD80 binding led to targeted ubiquitination and lysosomal degradation while CD86 binding led to enhanced This study identified key differences in transendocytosis by CTLA-4 when activated by CD80 and CD86 ligands; whereby CD80 binding led to targeted ubiquitination and lysosomal degradation while CD86 binding led to enhanced](https://www.cytoskeleton.com/media/Feb_14_CS_image_2.gif)
This study identified key differences in transendocytosis by CTLA-4 when activated by CD80 and CD86 ligands; whereby CD80 binding led to targeted ubiquitination and lysosomal degradation while CD86 binding led to enhanced
![Treg-expressed CTLA-4 depletes CD80/CD86 by trogocytosis, releasing free PD-L1 on antigen-presenting cells | PNAS Treg-expressed CTLA-4 depletes CD80/CD86 by trogocytosis, releasing free PD-L1 on antigen-presenting cells | PNAS](https://www.pnas.org/cms/10.1073/pnas.2023739118/asset/547ddeea-0f25-4733-845a-d904ec0ce15c/assets/images/large/pnas.2023739118fig01.jpg)
Treg-expressed CTLA-4 depletes CD80/CD86 by trogocytosis, releasing free PD-L1 on antigen-presenting cells | PNAS
![Expression and Prognostic Value of CD80 and CD86 in the Tumor Microenvironment of Newly Diagnosed Glioblastoma | Canadian Journal of Neurological Sciences | Cambridge Core Expression and Prognostic Value of CD80 and CD86 in the Tumor Microenvironment of Newly Diagnosed Glioblastoma | Canadian Journal of Neurological Sciences | Cambridge Core](https://static.cambridge.org/binary/version/id/urn:cambridge.org:id:binary:20230419151805994-0638:S0317167122000051:S0317167122000051_fig3.png?pub-status=live)
Expression and Prognostic Value of CD80 and CD86 in the Tumor Microenvironment of Newly Diagnosed Glioblastoma | Canadian Journal of Neurological Sciences | Cambridge Core
![Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis | Genome Medicine | Full Text Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis | Genome Medicine | Full Text](https://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs13073-020-00756-z/MediaObjects/13073_2020_756_Fig5_HTML.png)
Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis | Genome Medicine | Full Text
![Figure 8 from Dominant Role of CD80–CD86 Over CD40 and ICOSL in the Massive Polyclonal B Cell Activation Mediated by LATY136F CD4+ T Cells | Semantic Scholar Figure 8 from Dominant Role of CD80–CD86 Over CD40 and ICOSL in the Massive Polyclonal B Cell Activation Mediated by LATY136F CD4+ T Cells | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/1228111f410b4705b3a54a3b7690184a13b6b7f3/10-Figure8-1.png)
Figure 8 from Dominant Role of CD80–CD86 Over CD40 and ICOSL in the Massive Polyclonal B Cell Activation Mediated by LATY136F CD4+ T Cells | Semantic Scholar
![Frontiers | Dominant Role of CD80–CD86 Over CD40 and ICOSL in the Massive Polyclonal B Cell Activation Mediated by LATY136F CD4+ T Cells Frontiers | Dominant Role of CD80–CD86 Over CD40 and ICOSL in the Massive Polyclonal B Cell Activation Mediated by LATY136F CD4+ T Cells](https://www.frontiersin.org/files/Articles/17866/fimmu-03-00027-r2/image_m/fimmu-03-00027-g008.jpg)
Frontiers | Dominant Role of CD80–CD86 Over CD40 and ICOSL in the Massive Polyclonal B Cell Activation Mediated by LATY136F CD4+ T Cells
![In Vivo Imaging of Local Inflammation: Monitoring LPS-Induced CD80/CD86 Upregulation by PET | Molecular Imaging and Biology In Vivo Imaging of Local Inflammation: Monitoring LPS-Induced CD80/CD86 Upregulation by PET | Molecular Imaging and Biology](https://media.springernature.com/m685/springer-static/image/art%3A10.1007%2Fs11307-020-01543-3/MediaObjects/11307_2020_1543_Fig2_HTML.png)
In Vivo Imaging of Local Inflammation: Monitoring LPS-Induced CD80/CD86 Upregulation by PET | Molecular Imaging and Biology
![CD28 is constitutively expressed on T cells and CD86 is expressed on... | Download Scientific Diagram CD28 is constitutively expressed on T cells and CD86 is expressed on... | Download Scientific Diagram](https://www.researchgate.net/publication/7904322/figure/fig3/AS:294410890825742@1447204434354/CD28-is-constitutively-expressed-on-T-cells-and-CD86-is-expressed-on-antigen-presenting.png)